Comparative Metabolic Flux Profiling of Melanoma Cell Lines
نویسندگان
چکیده
منابع مشابه
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.
Metabolic rewiring is an established hallmark of cancer, but the details of this rewiring at a systems level are not well characterized. Here we acquire this insight in a melanoma cell line panel by tracking metabolic flux using isotopically labeled nutrients. Metabolic profiling and flux balance analysis were used to compare normal melanocytes to melanoma cell lines in both normoxic and hypoxi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2011
ISSN: 0021-9258
DOI: 10.1074/jbc.m111.282046